Seite 4 – CureVac

Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection

25. November 2012Mechanism of Action,Prophylactic Vaccines

Developing mRNA-vaccine technologies

12. Oktober 2012Review Articles,Oncology,Prophylactic Vaccines

Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect

1. Juni 2012Mechanism of Action,Oncology

Protein expression from exogenous mRNA: Uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway

1. Juli 2011Mechanism of Action

mRNA: delivering an antitumor message

1. Mai 2011Review Articles,Oncology

Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity

1. Januar 2011Mechanism of Action,Oncology

Intradermal Vaccinations With RNA Coding for TAA Generate CD8(+) and CD4(+) Immune Responses and Induce Clinical Benefit in Vaccinated Patients

28. Dezember 2010Clinical Data,Oncology

Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients

1. Juni 2009Clinical Data,Oncology

Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent

1. August 2007Mechanism of Action

Therapeutic anti-tumor immunity triggered by injections of immunostimulating single-stranded RNA

1. Oktober 2006Mechanism of Action,Oncology