Mechanism of Action Archives - Seite 2 von 3 - CureVac

Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection

Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect

Protein expression from exogenous mRNA: Uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway

Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity

Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent

Therapeutic anti-tumor immunity triggered by injections of immunostimulating single-stranded RNA

Characterization of the ribonuclease activity on the skin surface

Human peripheral blood mononuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro

Production and characterization of amplified tumor-derived cRNA libraries to be used as vaccines against metastatic melanomas

Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA